if there are any important limits we should really collect them, write them down, and find weird workarounds, like we did for the "SSD" topic.
1) Anything modern will have the wrong interface connector
IDE drives more modern than ATA133 and newer than 2005?
in dont think so.
there are some with 44 pin connectors though, probably rare, but possible to run into one if someone does not know what to look for.
there is a bunch of reasons for having a working internal drive, but there are also 20 dollar drives in the "slim external DVD burner" category.
haven´t yet seen one in a proper macmini design, but there are white or silver ones.
on the pro side you can add a second SSD if you remove that noisy, stinky combo apparatus.